Are you looking to configure Drupal with nginx Server? Here is how you build nginx from source with php upload progress module in ubuntu.
Create a directory nginx-src and change to that directory
mkdir nginx-src
cd nginx-src
Then download the source package via apt
PHP
Drupal allows very fine grained control over how content is presented to the end user. The presentation layer is abstracted beautifully and cleanly designed hooks allows for moving data from the logic layer to the presentation layer. The template file that handles the basic page layout of every drupal site is page.tpl.php and the different regions available for a given theme are all available as HTML elements in page.tpl.php. Another important template file is node.tpl.php which decides how nodes are presented to the end user.
Most of the web based systems that we build at Zyxware uses Drupal as the content framework. The following are the steps involved in setting up Apache, PHP, MySQL and Drupal on a freshly installed Ubuntu 8.04 system. If you follow the instructions you should be able to set it up as is but if you face problems let us know and we will try to help you.